Detalhe da pesquisa
1.
Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent ß-amyloid generation.
Cell
; 147(3): 615-28, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22036569
2.
Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
J Neurosci
; 42(8): 1574-1586, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987110
3.
Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease.
J Biol Chem
; 298(6): 101960, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452678
4.
Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline.
Acta Neuropathol
; 147(1): 4, 2023 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38133681
5.
Loss of TDP-43 in male germ cells causes meiotic failure and impairs fertility in mice.
J Biol Chem
; 297(5): 101231, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599968
6.
Early detection of Alzheimer's disease using creatine chemical exchange saturation transfer magnetic resonance imaging.
Neuroimage
; 236: 118071, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33878375
7.
Brain metabolism in tau and amyloid mouse models of Alzheimer's disease: An MRI study.
NMR Biomed
; 34(9): e4568, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050996
8.
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
Nature
; 525(7567): 129-33, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308899
9.
Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI.
Neuroimage
; 188: 380-390, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553917
10.
Amyloid precursor protein processing and Alzheimer's disease.
Annu Rev Neurosci
; 34: 185-204, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21456963
11.
Splicing repression is a major function of TDP-43 in motor neurons.
Acta Neuropathol
; 138(5): 813-826, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31332509
12.
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.
Proc Natl Acad Sci U S A
; 113(47): E7580-E7589, 2016 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27834214
13.
Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration.
Hum Mol Genet
; 24(8): 2228-40, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25552654
14.
Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.
Acta Neuropathol
; 133(6): 923-931, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28332094
15.
Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease.
J Neurosci
; 35(32): 11346-57, 2015 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269641
16.
Depletion of TDP-43 decreases fibril and plaque ß-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.
Acta Neuropathol
; 132(6): 859-873, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27785573
17.
Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.
Acta Neuropathol
; 131(3): 465-80, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26744351
18.
Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.
J Neurochem
; 130(1): 4-28, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24646365
19.
Differentiation of an embryonic stem cell to hemogenic endothelium by defined factors: essential role of bone morphogenetic protein 4.
Development
; 138(13): 2833-43, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21613326
20.
Fluid biomarkers for amyotrophic lateral sclerosis: a review.
Mol Neurodegener
; 19(1): 9, 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38267984